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Opening Bills vs Jaguars Odds for Wild Card Round

  • The Buffalo Bills will visit the Jacksonville Jaguars in the 2026 Wild Card Round
  • The Jaguars are riding an NFL-best eight-game win streak but the Bills are slight road favorites
  • See the opening Bills vs Patriots odds, including spread, total, and moneyline for the Wild Card Round

Arguably the best game of the 2026 Wild Card Round sees the Buffalo Bills (12-5, 5-3 away) visiting the Jacksonville Jaguars (13-4, 7-2 home) at EverBank Stadium.

The teams didn’t meet this year. Buffalo hammered Jacksonville 47-10 at home back in the 2024 regular season.

The opening Bills/Jaguars line establishes Buffalo as a slight road favorite.

Opening Bills vs Jaguars Odds for Wild Card Round

Market Bills Jaguars
Spread -1.5 (-105) +1.5 (-115)
Moneyline -112 -104
Total O 50.5 (-105) U 50.5 (-115)

SBD’s NFL odds page will list up-to-the-minute odds for all postseason games (juxtaposed with the opening lines). The NFL public betting splits page will show which side the betting public favors against the spread, total, and moneyline.

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The next table compares the Bills and Jaguars regular-season statistics.

BUF Bills vs JAX Jaguars Statistical Comparison

Bills Statistic Jaguars
27.9 (5th) Points Per Game 27.9 (6th)
21.0 (11th) Points Allowed Per Game 19.8 (9th)
370.3 (4th) Yards Per Game 337.4 (11th)
289.9 (7th) Yards Allowed Per Game 303.6 (11th)
+1 (12th) Turnover Differential +13 (3rd)
111.38 (4th) Total EPA 18.42 (14th)
5th O-DVOA Rank 15th
22nd D-DVOA Rank 7th

The Bills are the stronger team by most metrics. One area where the Jaguars stand out as having a big edge is turnover differential, where they finished +12 ahead of Buffalo. Unfortunately for the Jags, turnover differential has long proved to be one of the least-sustainable statistics. Jacksonville’s turnover “luck” is bound to regress over time.

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The post Opening Bills vs Jaguars Odds for Wild Card Round appeared first on Sports Betting Dime.



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